The Sharks faced off against the defending champions, Brisbane, putting up a valiant fight but ultimately losing 22-16 at Ocean Protect Stadium.
Despite the defeat, Cronulla showcased significant improvement, demonstrating they can compete with the league's elite, even during Ellie Johnston's milestone match.
Tamika Upton, potentially the best player in the NRLW, netted a hat trick, supported by the strong kicking game of Broncos halfback Jesse Southwell.
The match began with the Broncos posing an immediate threat, yet a crucial play from Johnston helped save a try under the posts.
Brisbane drew first blood with a well-executed set play; Ali Brigginshaw's high kick allowed Upton to sprint through and score, with Southwell adding the conversion for a 6-0 lead.
Hooker Quincy Dodd's break and Jada Taylor's follow-up set up the Sharks for a promising attacking opportunity.
In the 17th minute, a rapid play the ball and a slick pass from Chantay Kiria-Ratu enabled Georgia Ravics to score in the corner, though Kiria-Ratu's conversion attempt fell short.
Although behind, the Sharks maintained momentum, capitalizing on Brisbane's errors to advance downfield.