Isaah Yeo appears set to play through a pectoral injury and represent Australia at the Rugby League World Cup.
Meanwhile, a reported knee injury has strengthened Reece Walsh's chances of keeping his Kangaroos fullback position.
The Daily Telegraph reports Penrith's Dylan Edwards suffered a PCL injury in the Panthers' preliminary-final loss to the Knights.
He played through much of the second half but is expected to undergo surgery before next season and miss the World Cup.
Coach Kevin Walters must decide who will wear the No.1 jersey after the NRL grand final, with the squad announcement due Monday.
Walsh is the incumbent and is expected to be available, despite missing the end of Brisbane's season with an ankle injury.
James Tedesco has another chance to press his case in the grand final, where the Roosters face the Knights.
The Roosters captain held the Australian fullback jersey for six years, and a strong performance could influence selectors.
On Fanatics TV, reporter James Hooper said: "If Tedesco carves it up on Sunday, and he does win the Clive Churchill Medal, I think the selectors…they will say, 'Listen…we've got to go with Teddy.'"
Hooper added: "Me personally, I would go with Edwards,"
Walsh and Tedesco could both be selected as fullback cover. Roosters halfback Sam Walker may also contend for a starting spot.
Nathan Cleary is ruled out after breaking his leg, and Walker could partner Cameron Munster in the halves.