The Canberra Raiders travel west to Perth's Optus Stadium to meet the South Sydney Rabbitohs in a double-header.
Winger Xavier Savage faces an eight-week layoff after an ankle injury against the Knights, with Jed Stuart stepping into the starting line-up for his first appearance this season.
Souths arrive buoyant after overpowering the Bulldogs on Good Friday and welcome back Brandon Smith as an unchanged squad targets the top of the ladder.
Canberra need a morale-boosting victory to arrest their slide and begin climbing the standings against a top-four opponent.
The two clubs last met in Round 14 of the 2025 season when the Raiders beat the Rabbitohs 36-12.
A centre showdown between Simi Sasagi and Latrell Mitchell looms as a pivotal clash with both players intent on inspiring their teams.
Sasagi impressed against the Knights with the most runs and line breaks for Canberra, scoring under the posts and producing a try-saving tackle to deny Sandon Smith.