Canberra delivered a stunning 48-4 victory over the Bulldogs, while Wests Tigers edged the Knights 27-26 with a late field goal in a thrilling match.
With three rounds remaining, the Raiders (fourth) and Wests Tigers (third) are nearly assured spots in this season's six-team finals, a first for both teams.
They will clash at Campbelltown Sports Stadium next Sunday in a highly anticipated match.
On Saturday, the Raiders dominated at Belmore Sports Ground, with their forwards setting a solid foundation, allowing stars Zahara Temara and Krystal Blackwell to shine.
Having secured consecutive wins against premiers Brisbane and Newcastle, the Raiders took control early, with Simaima Taufa scoring in just the third minute.
Following tries from Mackenzie Wiki, Krystal Blackwell (two), and Isabella Waterman, they went to halftime ahead 28-0.
The second half began similarly, as Elise Simpson, Leianne Tufuga, and Blackwell each found the end zone in the first ten minutes, dousing any chance of a Bulldogs comeback.
Blackwell's three tries marked the first hat-trick in NRLW history for Canberra.
The Bulldogs currently sit eighth on the ladder and must quickly improve to have any shot at their first finals appearance.
Earlier, at McDonald Jones Stadium, Wests Tigers survived a fierce comeback from the Knights, winning 27-26 thanks to a field goal from Raecene McGregor with two minutes remaining.
This marked the Tigers' fourth straight win as they build momentum toward the season's end.
The match kicked off dramatically, with Wests scoring through Shaylee Bent just 44 seconds in.
Follow-up tries by Caitlin Turnbull, Harmony Crichton, and Shaniece Monschau gave the Tigers a 20-6 halftime lead after Tenika Willison scored for the Knights.
Losana Lutu extended the lead early in the second half, but the Knights responded with tries from Mercedez Taulelei-Siala, Sidney Taylor, and Olivia Higgins, tying the game with a penalty from Kirra Dibb three minutes toward the end.
Then, McGregor calmly nailed the decisive field goal, scoring seven points overall to elevate her season total to 65 and set the club's all-time NRLW points record, breaking Pauline Piliae-Rasabale's previous mark.
In a late match at Allianz Stadium, Charlize Lloyd-Phillips showcased her skill with a hat-trick, leading North Queensland to a 32-28 victory over the St George Illawarra Dragons.
Both teams found the end zone six times, but Rosie Kelly's four conversions gave the Cowboys an edge.
Lloyd-Phillips scored her first try in the seventh minute, added another in the 33rd, and completed her hat-trick in the 55th minute, solidifying the Cowboys' ninth-place position.
The Dragons remain last with just one win this season, featuring six different try-scorers.