Project Blue, a community initiative in Los Angeles, is backed by US sports teams the LA Rams and Los Angeles Lakers.
The Sydney Roosters will send Sam Walker, Mark Nawaqanitawase and Spencer Leniu to take part in the project in Compton next week, the Sydney Morning Herald reported.
The club has won the NRL premiership and is expanding its presence in the American market, where it owns the LA Roosters rugby league franchise.
Nawaqanitawase has permission to travel from his current club in Japanese rugby, while Leniu, an incoming Parramatta forward, has also been cleared to go.
Walker is making the California trip despite growing uncertainty about his immediate future at the Roosters.
The club is also reportedly interested in staging a fixture in Japan to open the 2028 NRL season.
The Roosters are tipped to face the Brisbane Broncos, a Queensland powerhouse, in that proposed match.